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抗病毒治疗对乙肝患者抗结核药物肝损伤的作用观察
引用本文:黄正辉,阮连国.抗病毒治疗对乙肝患者抗结核药物肝损伤的作用观察[J].临床肺科杂志,2011,16(12):1896-1898.
作者姓名:黄正辉  阮连国
作者单位:1. 430071 湖北武汉,武汉大学;430023 湖北武汉,武汉市医疗救治中心南五病区
2. 武汉市医疗救治中心南五病区, 湖北武汉,430023
摘    要:目的乙型肝炎合并肺结核的患者在抗结核化疗过程中,辅以抗病毒、护肝治疗的效果观察。方法将乙型肝炎合并肺结核患者56例,随机分为2组:抗结核+抗病毒治疗+护肝治疗组(A组);抗结核+护肝治疗组(B组),观察肝功能情况。结果 B组ALT、AST和T-BIL、HBV-DNA高于A组,两者差异显著(P〈0.05);B组肝功能异常率高于A组,两者差异显著(P〈0.05);B组停药率高于A组,两者差异显著(P〈0.05)。结论抗病毒治疗能明显减轻乙型肝炎合并肺结核的患者抗结核治疗引起的肝功能损害,减少抗结核治疗的停药率。

关 键 词:肺结核  乙型病毒性肝炎  抗病毒

Observation of hepatitis B patients' liver damage caused by anti - TB treatment during his antiretroviral therapy
HUANG Zheng-hui,RUAN Lian-guo.Observation of hepatitis B patients' liver damage caused by anti - TB treatment during his antiretroviral therapy[J].Journal of Clinical Pulmonary Medicine,2011,16(12):1896-1898.
Authors:HUANG Zheng-hui  RUAN Lian-guo
Institution:HUANG Zheng-hui,RUAN Lian-guo(Wuhan Medical Treatment Center,Wuhan 430023,China)
Abstract:Objective To study whether a TB patient with hepatitis B treated by antituberculotic should be hospitalized for the observation in order to achieve antibiral and protection of liver at the same time.Methods 56 TB patients with hepatitis B were divided into two groups and their damage of liver function were observed.Group A: lariatin+antivirus+protection of liver;Group B:lariatin+protection of liver.Results The observational measures of ALT,AST,T-BIL and HBV-DNA in was higher in Group B than those in Group A...
Keywords:tuberculosis  hepatitis B  Anti-virus  
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