| 头孢美唑对肺炎克雷伯菌的体外抗菌作用研究 |
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| 引用本文： | 王暖,陈晋,陈慧萍,孙立山.头孢美唑对肺炎克雷伯菌的体外抗菌作用研究[J].临床肺科杂志,2011,16(12):1857-1858. |
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| 作者姓名： | 王暖 陈晋 陈慧萍 孙立山 |
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| 作者单位： | 1. 同济大学医学院附属上海市肺科医院检验科, 上海,200433
2. 同济大学医学院附属东方医院检验科, 上海,200120 |
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| 摘 要： | 目的评价头孢美唑对肺炎克雷伯菌的体外抗菌作用。方法采用纸片扩散法确证试验检测ESBLs,K-B法测定头孢美唑对肺炎克雷伯菌的体外抗菌作用。结果 1258株肺炎克雷伯菌中产ESBLs94株,头孢美唑对肺炎克雷伯菌产ES-BLs株和非产ESBLs株均具有良好的抗菌作用。头孢美唑对产ESBLs株的体外敏感率为87.2%,优于测试的青霉素类、第一、第二代头孢菌素和喹诺酮类抗生素;但低于亚胺培南、厄他培南及哌拉西林-他唑巴坦;与阿米卡星、头孢匹肟和头孢替坦敏感性相近。结论头孢美唑钠对ESBLs稳定,对肺炎克雷伯菌具有良好的抗菌作用。
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| 关 键 词： | 肺炎克雷伯菌 头孢美唑 超广谱β-内酰胺酶 |
Invitro activity of cefmetazole against Klebsiella pneumoniae isolates |
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| WANG Nuan,CHEN Jin,CHEN Huiping,et al..Invitro activity of cefmetazole against Klebsiella pneumoniae isolates[J].Journal of Clinical Pulmonary Medicine,2011,16(12):1857-1858. |
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| Authors: | WANG Nuan CHEN Jin CHEN Huiping |
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| Institution: | WANG Nuan1,CHEN Jin1,CHEN Huiping1,et al.1.Department of Clinical Laboratory,Shanghai Lung Hospital,Tongji University School of Medicine,Shanghai 200433,2.Department of Clinical Laboratory,Shanghai East Hospital,Shanghai 200120,China |
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| Abstract: | Objective To evaluate the invitro antimicrobial activity of Cefmetazole against Klebsiella pneumoniae isolates.Methods BioMerieux VITEK-2(France) automated analysis system was used for bacteria differentiation and drug susceptibility test,the ESBLs producing st rains detected by diffusion confirmed test,antimicrobial susceptibility testing was done by K-B method.Results Of the 1258 strains tested,94 produced ESBLs.Cefmetazole had excellent antibacterial activity against both ESBLs-positive and ESBLs-negativ... |
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| Keywords: | Klebsiella pneumoniae Cefmetazole extended spectrum β lactamases |
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