| 表观扩散系数值鉴别儿童后颅窝肿瘤的价值 |
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| 引用本文： | 季学满,张宗军,卢光明,毕俊,袁彩云,王俊鹏,贾传海.表观扩散系数值鉴别儿童后颅窝肿瘤的价值[J].临床放射学杂志,2011,30(9). |
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| 作者姓名： | 季学满 张宗军 卢光明 毕俊 袁彩云 王俊鹏 贾传海 |
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| 作者单位： | 210002,南京军区南京总医院医学影像科 |
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| 基金项目： | 国家重点基础研究发展计划(973计划)项目(2006CB705707) |
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| 摘 要： | 目的评价MRI表观扩散系数(ADC)值在儿童小脑常见后颅窝肿瘤的鉴别诊断价值。资料与方法 43例经临床治疗及手术病理证实的儿童后颅窝肿瘤患者中,髓母细胞瘤24例,毛细胞型星形细胞瘤10例,室管膜瘤9例。所有患者行常规MRI、扩散加权成像(DWI)及增强MRI检查,在重组的ADC图像上比较肿瘤实质与正常小脑实质的信号强度,定量测定肿瘤实质区的ADC值。三组肿瘤实质的ADC值比较采用Wilcoxon秩和检验。结果 ADC图像上24例髓母细胞瘤中,9例肿瘤呈低信号、12例呈略低信号、3例呈等信号;肿瘤实质的平均ADC值为(0.70±0.11)×10-3mm2/s。所有10例毛细胞型星形细胞瘤均呈高信号,肿瘤实质的平均ADC值为(1.80±0.30)×10-3mm2/s。9例室管膜瘤中,5例肿瘤呈略高信号、4例呈高信号;肿瘤实质的平均ADC值为(1.16±0.18)×10-3mm2/s。髓母细胞瘤较毛细胞型星形细胞瘤的ADC值减低,差异有统计学意义(Z=-4.54,P值(0.01)。髓母细胞瘤较室管膜瘤的ADC值减低,差异有统计学意义(Z=-4.29,P值(0.01)。毛细胞型星形细胞瘤较室管膜瘤的ADC值增高,差异...
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| 关 键 词： | 脑肿瘤 星形细胞瘤 髓母细胞瘤 磁共振成像 扩散加权成像 |
The Value of Apparent Diffusion Coefficient in Differentiation of Pediatric Posterior Fossa Tumors |
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| JI Xueman,ZHANG Zongjun,LU Guangming,et al..The Value of Apparent Diffusion Coefficient in Differentiation of Pediatric Posterior Fossa Tumors[J].Journal of Clinical Radiology,2011,30(9). |
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| Authors: | JI Xueman ZHANG Zongjun LU Guangming |
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| Institution: | JI Xueman,ZHANG Zongjun,LU Guangming,et al.Department of Medical Imaging,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing 210002,P.RChina |
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| Abstract: | Objective To assess the utility of apparent diffusion coefficient(ADC) for differential diagnosis of common pediatric posterior possa tumors.Materials and Methods In 43 pediatric patients with surgically and pathologically confirmed posterior possa tumors,there were 24 medulloblastomas,10 pilocytic astrocytomas,and 9 ependymomas.All pediatric patients recevied conventional MRI,DWI and contrast enhanced MRI examination,the signal intensity of tumor parenchyma was compared with that of normal cerebellar paren... |
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| Keywords: | Cerebral neoplasms Astrocytoma Medulloblastoma Magnetic resonance imaging Diffusion-weighted imaging |
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