| 磁共振扩散加权成像在肝外胆管癌诊断中的应用研究 |
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| 引用本文： | 王余,王海平,彭鹏,马梦华,韩德昌.磁共振扩散加权成像在肝外胆管癌诊断中的应用研究[J].临床放射学杂志,2011,30(10). |
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| 作者姓名： | 王余 王海平 彭鹏 马梦华 韩德昌 |
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| 作者单位： | 1. 063000,河北省唐山市工人医院MR室
2. 063000,河北省唐山市工人医院肝胆外科 |
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| 基金项目： | 2010年唐山市科学技术研究与发展计划指导项目(编号:10130251a) |
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| 摘 要： | 目的探讨MR扩散加权成像(DWI)及表观扩散系数(apparent diffusion coefficient,ADC)值对肝外胆管癌的诊断价值。资料与方法回顾性分析58例经手术病理证实的肝外胆管癌患者的MRI原始资料,包括不同b值的DWI(b值为100 s/mm2、300 s/mm2、500 s/mm2、800 s/mm2、1000 s/mm2)及常规MRI平扫(T2WI、T1WI)。测量不同b值时肝外胆管癌病灶ADC值,计算病灶与正常肝脏间对比噪声比(CNR),根据HE染色病理图片记录肝外胆管癌细胞密度,并进行分析。结果 DWI对肝外胆管癌病灶的信号显示优于T2WI及T1WI。随着b值的增大,病灶ADC值逐渐降低,病灶与正常肝脏间CNR呈逐渐下降趋势,差异有统计学意义(P<0.05)。不同b值时,肝外胆管癌病灶ADC值与细胞密度之间均呈负相关(P<0.05);b=800 s/mm2时,其相关性最高(r=-0.81,P<0.05)。结论 DWI能较清楚地显示肝外胆管癌病灶,b值为800 s/mm2时最佳,与ADC值测量共同分析,有助于肝外胆管癌病灶的检出。
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| 关 键 词： | 磁共振成像 胆管癌 扩散加权成像 表观扩散系数 |
The Application of Diffusion Weighted Imaging in Diagnosing Extrahepatic Cholangiocarcinoma |
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| WANG Yu,WANG Haiping,PENG Peng,et al..The Application of Diffusion Weighted Imaging in Diagnosing Extrahepatic Cholangiocarcinoma[J].Journal of Clinical Radiology,2011,30(10). |
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| Authors: | WANG Yu WANG Haiping PENG Peng |
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| Institution: | WANG Yu,WANG Haiping,PENG Peng,et al. Department of MRI,Tangshan Worker's Hospital,Tangshan,Hebei Province 063000,P.R.China |
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| Abstract: | Objective To evaluate the values of diffusion weighted imaging(DWI) and apparent diffusion coefficient(ADC) in diagnosing extrahepatic cholangiocarcinoma.Materials and Methods Fifty-eight patients with extrahepatic cholangiocarcinoma proved by operation and pathology performed DWI(b=100s/ mm2,300s/ mm2,500s/ mm2,800s/ mm2,1000 s/ mm2,respectively) and routine MRI(T2WI,T1WI) examination.The ADC value of extrahepatic cholangiocarcinoma,contrast-noise ratio(CNR)of lesion and normal liver were measured respecti... |
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| Keywords: | Magnetic resonance imaging Cholangiocarcinoma Diffusion weighted imaging Apparent diffusion coefficient |
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