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夜间无创正压通气治疗COPD并Ⅱ型呼吸衰竭患者的临床研究
引用本文:颜新彦,王寅,陆亚莉,高爱武,杨林兴.夜间无创正压通气治疗COPD并Ⅱ型呼吸衰竭患者的临床研究[J].临床肺科杂志,2011,16(12):1856-1857.
作者姓名:颜新彦  王寅  陆亚莉  高爱武  杨林兴
作者单位:保定市第二医院呼吸科, 河北保定,071000
摘    要:目的探讨夜间无创正压通气(NPPV)治疗AECOPD合并Ⅱ型呼吸衰竭患者的临床疗效。方法选择82例AE-COPD合并Ⅱ型呼吸衰竭住院患者,随机分为夜间通气组(A组)、日间通气组(B组),治疗前及治疗后3 d、7 d清晨分别抽取动脉血查血气分析,比较治疗前后两组患者动脉血气分析变化。结果两组在治疗后血气分析各项指标较治疗前有明显改善,比较有显著差异(P〈0.05)。两组间治疗后比较A组PH、PaO2较B组明显升高,PaCO2明显降低,有显著差异(P〈0.05)。结论夜间NPPV治疗AECOPD合并Ⅱ型呼吸衰竭患者能较快改善患者血气分析指标及预后,长期应用有望提高患者生活质量。

关 键 词:慢性阻塞性肺疾病  Ⅱ型呼吸衰竭  夜间无创正压通气

Study of nocturnal non-invasive Bi-level positive airway pressure ventilation in chronic obstructive pulmonary disease and hypercapnic respiratory failure
YAN Xin-yan,WANG Yin,LU Ya-li,GAO Ai-wu,YANG Lin-xing.Study of nocturnal non-invasive Bi-level positive airway pressure ventilation in chronic obstructive pulmonary disease and hypercapnic respiratory failure[J].Journal of Clinical Pulmonary Medicine,2011,16(12):1856-1857.
Authors:YAN Xin-yan  WANG Yin  LU Ya-li  GAO Ai-wu  YANG Lin-xing
Institution:YAN Xin-yan,WANG Yin,LU Ya-li,GAO Ai-wu,YANG Lin-xing Deparment of Respiratory Medicine,Baoding No.2 Hospital,He Bei 071000,China
Abstract:Objective To investigate the clinical effect of nocturnal noninvasive positive pressure ventilation in the treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD) with hypercapnic respiratory failure(HRF).Methods Eighty-two patients with AECOPD and HRF were randomly divided into nocturnal NPPV group(A) and NPPV group(B).Changes in artery blood gas were compared between the groups before and after the treatment.Results The blood gas analysis indexes of the both groups were significan...
Keywords:chronic obstructive pulmonary disease  hypercapnic respiratory failure  nocturnal non-invasive positive airway pressure ventilation  
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