胎盘免疫调节因子对妇科恶性肿瘤病人免疫功能的影响

目的：观察胎盘免疫调节因子（ＰＩＦ）对病人细胞免疫功能及体液免疫功能的影响，方法：利用ＰＩＦ治疗妇科恶性肿瘤６３例，并设对照组６３例。治疗组病人第天肌注ＰＩＦ４ｍ，３０ｄ为一疗程，对照组不注射ＰＩＦ。两组病人治疗前及治疗３０ｄ后抽血检测Ｔ淋巴细胞亚群（ＣＤ３、ＣＤ４、ＣＤ８）、ＮＫ细胞活性、淋巴细胞转化率（ＬＴ）及免疫球蛋白（ＩｇＡ、ＩｇＧ、ＩｇＭ）。结果：经ＰＩＦ治疗后，治疗组病人ＣＤ３、ＣＤ４

EFFECT OF PLACENTAL IMMUNOREGULATING FACTOR ON IMMUNO-LOGICAL FUNCTION OF PATIENTS WITH GYNECOLOGIC MALIGNANT TUMOR

Objective:To observe the therapeutic effect on immunological function of gynecologic malignant tumor patients treated with placental immunoregulating factor (PIF) Methods:PIF was used to treat 63 cases of gynecologic malignant tumor patients comparing with a control group of 63 cases of patients diagnosed similarly in the same period Patients in treating group were injetced with PIF 4 ml/day and the period of treatment was 30 days.The activity of NK cells, the CD 3 cells,the CD 4 cells,CD 4 /CD 8 ratio,the ratio of lymphocyte transforming (LT),IgA,IgG,IgM in the peripheral blood of two group patients were detected before PIF treatment and after treatment for 30 days.Results:After PIF treatment,the activity of NK cells,CD 3,CD 4,CD 4/CD 8,LT,IgA,IgG,IgM of the group in treatment significantly increased,and those indexes of control group decreased.Conclusions:PIF can obviously promote the immunological function of patients with gynecoloigic malignant tumor.