Use of re-randomized data in meta-analysis期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Use of re-randomized data in meta-analysis

Authors:	Iztok?Hozo author-information" > author-information__contact u-icon-before" > mailto:ihozo@iun.edu" title=" ihozo@iun.edu" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Benjamin?Djulbegovic,Otavio?Clark,Gary?H?Lyman

Affiliation:	(1) Department of Mathematics, Indiana University Northwest, Gary, IN, USA;(2) Interdisciplinary Oncology Program, H. Lee Moffitt Cancer Center and Research Institute at the University of South Florida, Tampa, FL, USA;(3) Instituto do Radium de Campinas, Av Heitor Penteado 1780, Campinas, SP, Brasil;(4) James P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester, NY, USA

Abstract:	Background Outcomes collected in randomized clinical trials are observations of random variables that should be independent and identically distributed. However, in some trials, the patients are randomized more than once thus violating both of these assumptions. The probability of an event is not always the same when a patient is re-randomized; there is probably a non-zero covariance coming from observations on the same patient. This is of particular importance to the meta-analysts.

Keywords:
本文献已被 SpringerLink 等数据库收录！