临床药师干预用药对老年脑梗死伴肺部感染患者临床抗感染治疗的影响

目的:考察临床药师干预用药对老年脑梗死伴肺部感染患者临床抗感染治疗的影响.方法:选取2018年1月-2019年1月间收治的老年脑梗死伴肺部感染患者46例临床资料为干预前组,另选取2019年2月-2020年1月间收治的老年脑梗死伴肺部感染患者46例临床资料为干预后组(由临床药师干预用药);分析干预前后脑梗死伴肺部感染患者...

Influence of Clinical Pharmacists' Intervention on Clinical Medication of Senile Cerebral Infarction Patients with Pulmonary Infection

Objective:To investigate the influence of clinical pharmacists'intervention on the clinical anti-infective medication of senile cerebral infarction patients with pulmonary infection.Methods:The clinical data of 46 senile cerebral infarction patients with pulmonary infection admitted from January 2018 to January 2019 were selected as the preintervention group,and the clinical data of 46 senile cerebral infarction patients with pulmonary infection admitted from February 2019 to January 2020 were selected as the post-intervention group(with intervention medication by clinical pharmacists).The changes of clinical infection indexes(body temperature,WBC,neutrophils,CRP),the distribution of pathogenic bacteria and the medication of anti-infective drugs were analyzed in patients of cerebral infarction with pulmonary infection before and after intervention.Results:92 patients were mainly infected by Acinetobacter baumannii(31.52%),followed by Enterobacter aerogenes and Escherichia coli(3.26%).After intervention,the clinical infection indexes(body temperature,WBC,neutrophilic granulocyte count,CRP)of the patients in the group were all lower than those in the group before intervention(P<0.05).The drug frequency(DDDs)of cefoperazone-sulbactam,etimicin and ceftazidime were 38.78,30.75 and 23.79,respectively.The DDDs of cefoperazone-sulbactam,piperacillin-sulbactam and etimicin were 37.63,17.45 and 13.68,respectively,in the group before intervention.Conclusion:Clinical pharmacists participated in clinical anti-infective medication for elderly patients of cerebral infarction with pulmonary infection,which effectively decreased inflammation indicators and improved the accuracy of anti-infective medication and the effectiveness of anti-infective drug therapy.