The influence of the alloy of megaprostheses on infection rate |
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| Authors: | Gosheger Georg Goetze Christian Hardes Jendrik Joosten Uwe Winkelmann Winfried von Eiff Christof |
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| Institution: | aDepartment of Orthopaedics, University Hospital of Münster, Münster Germany;bThe Department of Traumatology and Orthopaedic Surgery, Marienhospital, Osnabrueck, Germany;cInstitute of Medical Microbiology, University Hospital of Münster, Münster, Germany |
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| Abstract: | We retrospectively reviewed 197 patients who underwent reconstruction with a megaprosthesis of the lower extremity. A cobalt-chrome alloy system was used in 77 patients and a titanium alloy system in 120 patients. The overall infection rate was 20.8% (n = 41). Separated into the 2 prosthesis systems used, an infection rate of 31.2% was found in the patients with a cobalt-chrome-alloy prosthesis and 14.2% in the titanium alloy group of patients (P < .01). Early infection occurred in 5.1% (n = 10) and late infection in 15.7% (n = 31). Selecting 2 identical subgroups for further analysis, the cobalt-chrome alloy prostheses were associated with a significantly higher infection rate, with 5 infections of 26 megaprostheses vs 1 infection of 36 titanium megaprostheses (P < .05). |
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| Keywords: | megaprosthesis tumor endoprosthesis infection cobalt chrome titanium |
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