试论IgA肾病临床表现与肾脏病理的关系

目的临床分析IgA肾病患者的临床表现及肾脏病理关系。方法选取我院2011年8月至2012年8月收治的200例肾穿刺活检患者，给予B超肾活检、免疫检查、光镜检查，分析确诊的IgA临床特点与病理。结果经过检查后得知，有70例患者确诊为IgA肾病，其中15例肾病综合征、2例肾小球肾炎、9例血尿、17例隐匿性肾小球肾炎、25例慢性肾小球肾炎、1例肾功能不全、1例妊娠伴随慢性肾炎。病理类型：12例轻微病变、15例系膜增殖型、25例局灶节段性硬化、9例FSGS型、5例增生硬化型。结论针对IgA肾病患者，其临床表现和病理表现之间的严重程度不完全相符，实施肾活检，可有有效判断肾脏疾病病理类型，有利于确定治疗方案，改善预后。

the Relationship between IgA Nephropathy Clinical Manifestationand Renal Pathology

Objective Clinical analysis of the relationship between theclinical manifestation and renal pathology in patients with IgA nephropathy. Methods In our hospital from 2011 August to 2012August were treated 200 eases of renal biopsy in patients with B-mode ultrasonography, renal biopsy, immunological examination, light microscopy, IgA analysis of clinical eharaeteristies andpathologie diagnosis. Results After examination after that, of 70 patients diagnosed as IgA nephropathy, of which 15 cases of nephrotic syndrome, 2 eases of glomerulonephritis, 9 cases.of hematuria, 17 eases of Latent Glomerulonephritis, 25 eases of chronic glomerulonephritis, 1 eases of renal insufficiency, 1 cases of pregnancy with chronic nephritis. Pathological types： 12 cases ofrnild lesion, 15 eases of mesangial proliferative type, 25 eases of focal segmental sclerosis, 9 cases of type FSGS, 5 eases of-proliferative selerosing. Conclusion Patients with IgA nephropathy, the severity of the clinical manifestations andpathological findings between the not entirely consistent, implementation of renal biopsy, can effectively judge thepathological type of kidney disease, to determine the treatment, prognosis.