| 氢质子磁共振波谱对帕金森氏病的诊断价值 |
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| 引用本文： | 苗重昌,何银,史良玉. 氢质子磁共振波谱对帕金森氏病的诊断价值[J]. 河北医学, 2006, 12(11): 1114-1116 |
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| 作者姓名： | 苗重昌 何银 史良玉 |
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| 作者单位： | 江苏省连云港市第一人民医院影像科,江苏,连云港,222002;江苏省连云港市第一人民医院影像科,江苏,连云港,222002;江苏省连云港市第一人民医院影像科,江苏,连云港,222002 |
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| 摘 要： | 目的:探讨氢质子磁共振波谱(1H-MRS)对帕金森病的诊断价值。方法:通过对20例帕金森病患者和20例年龄相当的健康人豆状核磁共振波谱,分析豆状核N-乙酰天冬氨酸/肌酸(NAA/Cr)和胆碱/肌酸(Cho/Cr)比值的变化。结果:帕金森病患者豆状核NAA/Cr比值显著低于对照组相应感兴趣区(P<0.05),Cho/Cr比值显著高于对照组相应感兴趣区(P<0.05)。结论:1H-MRS是一种能够反映帕金森病患者神经病理学变化的无创技术。
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| 关 键 词： | 帕金森病 磁共振波谱 基底节区 豆状核 |
| 文章编号： | 1006-6233（2006）11-1114-03 |
Diagnostic Value on Pronton Magnetic Resonance Spectroscopy of Parkinson's Disease |
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| MIAO Zhong-chang,HE Yin,SHI Liang-yu. Diagnostic Value on Pronton Magnetic Resonance Spectroscopy of Parkinson's Disease[J]. Hebei Medicine, 2006, 12(11): 1114-1116 |
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| Authors: | MIAO Zhong-chang HE Yin SHI Liang-yu |
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| Affiliation: | The First Hospital of Lianyungang, Jiangsu Lianyungang 222002, China |
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| Abstract: | Objective: To assess the value of magnetic resonance spectroscopy(MRS) in Parkinson's disease(PD).Method: ~1H-MRS of putamina was observed in 20 patients with PD and 20 healthy age-matched controls.The changes of NAA/Cr and Cho/Cr ratio in the putamina were analyzed.Result: NAA/Cr ratios were reduced significantly and Cho/Cr ratios were increased significantly in the putamina of PD patients compared to those in putamina of healthy controls(P<0.05).Conclusion:~ 1H-MRS is a noninvasive technique that can reveal the pathological changes of nerve of PD patients. |
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| Keywords: | Parkinson's disease ~1H-MRS Basal ganglia Putamina |
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