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高频震荡通气技术研究现状分析与展望
引用本文:袁越阳,周理,刘炜,戴征(综述),陈宇清(审校). 高频震荡通气技术研究现状分析与展望[J]. 生物医学工程学杂志, 2021, 0(1): 185-190,195
作者姓名:袁越阳  周理  刘炜  戴征(综述)  陈宇清(审校)
作者单位:湖南城市学院机电工程学院;上海市胸科医院呼吸内科;湖南明康中锦医疗科技发展有限公司
基金项目:国家重点研发计划数字诊疗专项(2019YFC0121700);湖南省自然科学基金项目(2020JJ4159);湖南省教育厅重点研究项目(19A093);上海交通大学“交大之星”医工交叉研究基金(YG2019ZDB08)。
摘    要:以低平均气道压和小潮气量为主要特征的高频震荡通气(HFOV),自出现以来备受医务、科研人员的关注。本文就HFOV通气技术方面的研究现状与发展趋势进行了分析和展望,重点介绍与分析了有关HFOV的通气模型、通气机制和通气模式方面的研究现状。并藉此提出,在未来一段时期内,对HFOV通气技术的研究将主要集中在三个方面:建立多级、高阶、非线性的黏性阻力、惯性阻力和顺应性(RIC)通气模型;更为充分地揭示HFOV之所以能够有效通气的机制;研究实现低风险的无创HFOV。对HFOV通气技术的研究与发展,将为呼吸系统疾病患者提供一种不同于常频通气的通气方式。

关 键 词:高频震荡通气  通气模型  高频震荡通气机制  通气模式

Prospects and developments in the technologies of high frequency oscillatory ventilation
Affiliation:(School of Mechanical and Eectrical Engineering,Hunan City University,Yiyang,Hunan 413099,P.R.China;Department of Respiratory Medicine,Shanghai Chest Hospital,Shanghai 200030,P.R.China;Hunan Micomme Medical Development Co.,Ltd,Changsha 410000,P.R.China)
Abstract:The high frequency oscillatory ventilation(HFOV) is characterized with low tidal volume and low mean airway pressure, and can well support the breathing of the patients with respiratory diseases. Since the HFOV was proposed, it has been widely concerned by medical and scientific researchers. About the HFOV, this paper discussed its current research status and prospected its future development in technologies. The research status of ventilation model,mechanisms and ventilation mode were introduced in detail. In the next years, the technologies in developing HFOV will be focused on: to develop the branched high-order nonlinear or volume-depended resistance-inertance-compliance(RIC)ventilation model, to fully understand the mechanisms of HFOV and to achieve the noninvasive HFOV. The development in technologies of HFOV will be beneficial to the patients with respiratory diseases who failed with conventional mechanical ventilation as one of considerable ventilation methods.
Keywords:high frequency oscillation ventilation  ventilation model  mechanisms of high frequency oscillation ventilation  ventilation mode
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