河北农村乙型肝炎感染状况调查

这次在吴兴乡检测HBsAg、抗-HBc、抗-HBs和HBV感染的乙肝标志,整体人群检测2,169名。其阳性率分别为8.1%,31.1%,39.8%,56.9%;1~10岁儿童检测1,698名,阳性率分别为11.3%,36.0%,33.4%,54.3%。整体人群的HBsAg和抗-HBc都随年龄增加而递减(6.5%4.8%),但在1~4岁儿童和成人期间有二个高峰,且前者为高;而抗-HBs随年龄增加而递增(4.8%),HBV感染递增不明显(1.2%),也有二个高峰,但以成人高峰为高。10岁内儿童增减速度比成人快。在讨论中分析了HBV感染水平、三项乙肝感染标志的传染源作用和年龄感染高峰与增减速度,说明该农村乙肝感染严重,且有新增加趋势,为防治乙肝提供了科学论据。

The Prevalence of HBV in Rural Area of Hebei Province

In 1983, 2169 blood samples have been taken cfrom residents of the whole Wuxing area (including six villages) in Zhengding County of Hebei Province, to screen for the Presence of HBV markers. The results are shown as follows.
The HBV infection rate was found to be 56.9%. The HBsAg anti-HBc and anti-HBs were found to be 8.1%, 31.1% and 39.8% respectively.
The HBsAg and anti-HBc decreased Progressively with a rate of 6.5% and 4.8% respectively per 10 years The anti-HBs and the HBV infection rate increased successively at the rate of 4.8% and 1.2% every 10 years.
In children under 10, the HBsAg and anti-HBc decreased successively with a rate of 11.4% and 0.8% Per year, while the anti-HBs and HBV infection rate increased Progressively with a rate of 11.1% and 3.0% respetively per year.
There were two Peaks of the infection. One was in children of 1-4 year old group and the other adults at about 40 years old.
The viral hepatitie prevalence in 1983 was found to be 912/100,000.
The incidence rate/year was 91.3/100,000, and the Prevalence rate of HBV markers of the hepatitis cases was 85%.
The mortality rate/year from hepatic diseases was 20.6/100,000. 85.7% of the cases died from liver cancer and 5 of the six cases detected had HBsAg in their sera.