| 血必净注射液治疗脓毒症的系统评价 |
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| 引用本文： | 胡晶,商洪才,李晶,张俊华,张莉,张伯礼. 血必净注射液治疗脓毒症的系统评价[J]. 解放军医学杂志, 2010, 35(1) |
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| 作者姓名： | 胡晶 商洪才 李晶 张俊华 张莉 张伯礼 |
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| 作者单位： | 1. 天津中医药大学循证医学中心,天津,300193
2. 天津中医药大学中医药研究院,天津,300193 |
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| 摘 要： | 目的评价血必净注射液治疗脓毒症的疗效和安全性。方法系统检索Cochrane图书馆、PubMed、EMbase、CBM、CNKI和VIP数据库,全面收集血必净注射液治疗脓毒症的随机对照试验(RCT),并追查纳入文献后的参考文献。对文献进行质量评价,并采用Revman5.0软件进行统计分析。结果共纳入25篇文献,Meta分析结果显示:血必净注射液+常规治疗组的28d病死率[相对危险度(RR)=0.65,95%CI为0.54～0.79]、观察期间病死率[RR=0.42,95%CI为0.32～0.56]、平均住院天数[加权均数差(WMD)=-2.40,95%CI为-4.41～-0.38]、无效率(RR=0.37,95%CI为0.21～0.66)及并发症发生率均低于常规治疗组;治疗7d及14d后APACHEⅡ评分的改善情况均优于常规治疗组(WMD=3.74,95%CI为2.05～5.43;WMD=10.50,95%CI为1.43～19.57)。与生脉注射液+常规治疗组相比,血必净注射液+生脉注射液+常规治疗组的观察期间病死率、治疗7d后APACHEⅡ评分差异无统计学意义。血必净注射液+常规治疗组的观察期间病死率低于乌司...
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| 关 键 词： | 血必净注射液 脓毒症 Meta分析 |
XUEBIJING injection for sepsis: a comprehensive review |
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| HU Jing,SHANG Hong-cai,LI Jing,ZHANG Jun-hua,ZHANG Li,ZHANG Bo-li. XUEBIJING injection for sepsis: a comprehensive review[J]. Medical Journal of Chinese People's Liberation Army, 2010, 35(1) |
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| Authors: | HU Jing SHANG Hong-cai LI Jing ZHANG Jun-hua ZHANG Li ZHANG Bo-li |
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| Abstract: | Objective To assess the efficacy and safety of XUEBIJING injection in the treatment of sepsis.Methods All reports of trial of XUEBIJING injection in the treatment of sepsis were retrieved from database of Cochrane Library,PubMed,EMbase,China Biomedicine Database(CBM),China National Knowledge Infrastructure(CNKI)and VIP,and the references of eligible studies were also screened.The methodological quality of included studies was evaluated,and the Cochrane Collaboration's RevMan 5.0 was used for data analysis.R... |
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| Keywords: | XUEBIJING injection sepsis Meta-analysis |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
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