| SPECT观察兔肺撞击伤伤情演变的实验研究 |
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| 引用本文： | 吴秋平,蒋耀光,陈邦菊,闵家新. SPECT观察兔肺撞击伤伤情演变的实验研究[J]. 第三军医大学学报, 2005, 27(6): 474-476 |
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| 作者姓名： | 吴秋平 蒋耀光 陈邦菊 闵家新 |
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| 作者单位： | 第三军医大学,新桥医院胸外科,重庆,400037;第三军医大学,大坪医院野战外科研究所胸心外科,重庆,400042 |
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| 基金项目： | 重庆市科委资助项目(2002)~~ |
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| 摘 要： | 目的 比较研究声门紧闭与开放状态下兔肺撞击伤的伤情变化规律。方法 建立兔肺撞击伤模型,采用单 光子发射计算机断层显像(SPECT)对声门紧闭与开放状态下兔肺撞击后肺损伤伤情进行动态观察。结果 在伤后各时间 点,声门紧闭组撞击侧(右肺)ROI2 ROI1及非撞击侧(左肺)ROI3 ROI1比值显著高于声门开放组(P<0.05)。结论 声门 紧闭组的肺损伤程度大于声门开放组,SPECT不仅可以显示病灶的位置和大小,还可以早期对病情的发展提供有意义的 判定。
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| 关 键 词： | 胸部创伤 撞击伤 SPECT |
| 文章编号： | 1000-5404(2005)06-0474-03 |
| 修稿时间： | 2004-12-07 |
Development of lung impact injuries in rabbits by SPECT |
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| WU Qiu-ping,JIANG Yao-guang,CHEN Bang-ju,MIN Jia-xin. Development of lung impact injuries in rabbits by SPECT[J]. Acta Academiae Medicinae Militaris Tertiae, 2005, 27(6): 474-476 |
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| Authors: | WU Qiu-ping JIANG Yao-guang CHEN Bang-ju MIN Jia-xin |
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| Abstract: | Objective To compare the changes of lung impact injuries under the closed and open states of glottis. Methods The animal model of lung impact injuries was established. The development of lung impact injuries in the rabbit glottis under the closed and open states was observed by single photon emission computerized tomography (SPECT). Results ROI 2/ROI 1 ratios of both right and left lungs in the closure group were insignificantly higher than those in the open group at the designed time points (P<0.05). Conclusion The severity of lung injuries in the closed group is significantly higher than that in the open group under the same impact condition. SPECT can indicate the location and size as well as the changes of injury, and can hence provide valuable evaluation of the early development and treatment of the injuries. |
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| Keywords: | thoracic trauma impact injury single photon emission computerized tomography |
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