|
|||||
|
|
| Effect of Antisense Oligonucleotide to AnnexinⅡon the t-PA-mediated Plasmi nogen Activation in vitro | |
| 作者姓名： | 张晓晖 周华荣 夏凌辉 沈关心 胡豫 魏文宁 宋善俊 |
| 作者单位： | ZHANG Xiaohui，ZHOU Huarong，XIA Lin ghui，SHEN Guanxin，HU Yu，WEI Wenning，SONG Shanjun Institute of Hematology，Xiehe Hospital，Tongji Medical College，Huazhong Univer sity of Science and Technology，Wuhan 430030 * Institute of Immunolo |
| 摘 要： | Annexin ,a calcium- regulated,phospho-lipid- binding protein on endothelial cells,macrophages and some tumor cells,is a cell- sur-face co- receptor for both plasminogen( PL G) andits activator,tissue plasminogen activator ( t-PA ) [1] .Annexin contains three distinct func-tional regions:N- terminal region,C- terminal re-gion,and core region.The core region of annexin contains the Ca2 +- and phospholipid- bindingsites[2 ] .The C- terminal region contains the plas-minogen- binding domain a… |
| 关 键 词： | annexin Ⅱ antisense oligonucleotide plasmin ogen activation |
| 本文献已被 CNKI 等数据库收录！ | |