| DIFFERENTIATION OF PSEUDOCONDYLOMA OF VULVA AND CONDYLOMA ACUMINATA BY DOT BLOT HYBRIDIZATION AND POLYMERASE CHAIN REACTION |
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| 作者姓名： | 刘跃华 王家璧 司静懿 |
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| 摘 要： | ＤＩＦＦＥＲＥＮＴＩＡＴＩＯＮＯＦＰＳＥＵＤＯＣＯＮＤＹＬＯＭＡＯＦＶＵＬＶＡＡＮＤＣＯＮＤＹＬＯＭＡＡＣＵＭＩＮＡＴＡＢＹＤＯＴＢＬＯＴＨＹＢＲＩＤＩＺＡＴＩＯＮＡＮＤＰＯＬＹＭＥＲＡＳＥＣＨＡＩＮＲＥＡＣＴＩＯＮＬｉｕＹｕｅｈｕａ刘跃华；Ｗａｎｇ...
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| 关 键 词： | 杂交技术 聚合酶链反应 尖锐湿疣 假性疣 鉴别诊断 |
DIFFERENTIATION OF PSEUDOCONDYLOMA OF VULVA AND CONDYLOMA ACUMINATA BY DOT BLOT HYBRIDIZATION AND POLYMERASE CHAIN REACTION |
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| Liu Yuehua, Wang Jiabi and Si Jingyi.DIFFERENTIATION OF PSEUDOCONDYLOMA OF VULVA AND CONDYLOMA ACUMINATA BY DOT BLOT HYBRIDIZATION AND POLYMERASE CHAIN REACTION[J].Chinese Medical Sciences Journal,1996,11(1):53-55. |
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| Authors: | Liu Yuehua Wang Jiabi and Si Jingyi |
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| Abstract: | This study differentiated pseudocondyloma of vulva from condyloma acuminata using dot blot hybridization and polymerase chain reaction (PCR). A total of 27 cases of pseudocondyloma of vulva and 65 cases of condyloma acuminata were selected for the study. The genital lesions were examined clinically and were biopsied. Each biopsy was subjected to histological examination and HPV DNA analysis by dot blot hybridization and PCR. Dot blot analysis detected HPV DNA in 19(82. 6%) out of 23 cases of condyloma acuminata and 2(25% ) out of 8 cases pseudocondyloma of vulvae (P<0. 05). PCR detected HPV DNA in 51 (92. 7%) out of 55 cases of condyloma acuminata , compared with none in 23 cases of pseudocondyloma (P<0.001 ). HPV DNA was present in the majority of condyloma acuminata specimens. HPV 6 and 11 were the predominant types. Peudocondyloma is probably not associated with HPV. PCR was the most sensitive and useful technique for HPV DNA detection. |
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| Keywords: | pseudocondyloma condyloma acuminata polymerase chain reaction |
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