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吸烟对冠心病患者血浆同型半胱氨酸的影响
引用本文:郭炳彦,崔志宏,张延军,李拥军.吸烟对冠心病患者血浆同型半胱氨酸的影响[J].临床荟萃,2009,24(9):755-757.
作者姓名:郭炳彦  崔志宏  张延军  李拥军
作者单位:1. 河北医科大第二医院,心内科,河北,石家庄,050000;故城县医院,心内科,河北,故城,253800
2. 故城县医院,心内科,河北,故城,253800
3. 河北医科大第二医院,心内科,河北,石家庄,050000
摘    要:目的探讨吸烟对冠心病患者血浆同型半胱氨酸(HCY)的影响,为冠心病患者早期治疗提供依据。方法将所有研究对象分为4组:①冠心病吸烟组74例;②冠心痛不吸烟组46例;③健康吸烟组42例;④健康不吸烟组26例。又根据吸烟指数将所有入选的吸烟者分成3组:重度吸烟组40例、中度吸烟组44例和轻度吸烟组32例。采用酶联免疫吸附测定(ELISA)法检测血浆HCY水平。结果血浆HCY水平在冠心病吸烟组、冠心病不吸烟组、健康吸烟组、健康不吸烟组中依次降低(15.79±4.18)μmol/L、(12.12±2.43)μmol/L、(10.85±3.78)μmol/L、(7.26±3.15)μmol/L(P〈0.01),在健康不吸烟组、轻度吸烟组、中度吸烟组、重度吸烟组血浆HCY水平依次增高(7.26±3.15)μmol/L、(9.58±4.06)μmol/L、(13.32±3.26)μmol/L、(15.43±3.18)μmol/L(P〈0.01)。结论吸烟使冠心病患者和健康者血浆HCY水平升高,HCY水平随吸烟指数的增加而升高。

关 键 词:冠状动脉疾病  同型半胱氨酸  吸烟

Cigarette smoking on level of plasma homocysteine in patients with coronary artery disease
GUO Bing-yan,CUI Zhi-hong,ZHANG Yan-jun,LI Yong-jun.Cigarette smoking on level of plasma homocysteine in patients with coronary artery disease[J].Clinical Focus,2009,24(9):755-757.
Authors:GUO Bing-yan  CUI Zhi-hong  ZHANG Yan-jun  LI Yong-jun
Institution:GUO Bing-yan1,2,CUI Zhi-hong2,ZHANG Yan-jun2,LI Yong-jun11.Department of Cardiology,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,China,2.Department of cardiology,Gucheng County Hospital,Gucheng 253800
Abstract:Objective To explore the effect of cigarette smoking on level of plasma homocysteine(HCY) in patients with coronary artery disease(CAD) and provide evidence for early therapy of CAD.Methods A total of 120 patients with CAD were divided into two groups:the smoker group(74 cases) and the nonsmoker group(46 cases);68 healthy people were divided into two groups:the smoker group(42 cases) and the nonsmoker group(26 cases).According to the smoking index,all the smoking subjects were divided into three groups:heav...
Keywords:coronary artery disease  cigarette smoking  homocysteine  
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