不同方法治疗幽门螺杆菌相关性胃溃疡的效果分析

目的 探讨三联疗法治疗幽门螺杆菌（Hp）相关性胃溃疡的临床效果.方法 选取2012年1月～2013年1月在本院门诊就诊的Hp感染相关性胃溃疡患者125例为研究对象,随机将其分为观察组63例和对照组62例,观察组应用三联疗法治疗,对照组应用奥美拉唑治疗,两组患者疗程均为4周,观察两组患者的临床治疗效果及症状改善情况.结果 观察组临床总有效率为92.06％,对照组临床总有效率为75.80％,两组差异有统计学意义（P＜0.05）.观察组腹胀、嗳气、上腹疼痛、反酸缓解时间显著少于对照组,差异有统计学意义（P＜0.05）.结论 应用三联疗法治疗Hp感染相关性胃溃疡的临床效果显著,能在较短时间内缓解患者的临床症状,安全有效,值得临床应用.

Effect analysis of different treatment for gastric ulcer associated with Helicobacter pylori

Objective To investigate the clinical effect of triple therapy for gastric ulcer associated with Helicobacter pylori （Hp）.nethods 125 patients with gastric ulcer associated with Hp infection,treated in out-patient department of our hospital between January 2012 and January 2013,were selected as study object and randomly assigned into obser-vation group （63 cases） and control group （62 cases）,who were received triple therapy and omeprazole treatment for 4 weeks,respectively.The clinical therapeutic effect and improvement of symptoms of patients in both groups were ob- served.Results The clinical total effective rate of observation group and control group was respectively 92.06% and 75.80%,with significant difference （P〈O.OS）.The alleviating time of abdominal distention,belching,upper abdominal pain,acid reflux of patients in observation group were significantly shorter than those of patients in control group,with significant difference （P〈0.05）.Conclusion For gastric ulcer associated with Hp infection,the application of triple therapy has remarkable clinical effect,can alleviate patients＇ clinical symptoms in a relatively short time;it is safe,effective, and worthy of clinical application.