男性型脱发148例临床分析

目的探讨男性型脱发的临床特征。方法收集148例男性型脱发病例的临床资料,并对患者的发病年龄、家族史、临床分级、疗效、血清双氢睾酮(DHT)、轻拉试验进行分析。结果发病年龄以15～25岁占比例最大,家族史与发病年龄相关,家族史与临床分级相关,血清DHT水平升高占80.41%,非那雄胺治疗总有效率为88.98%,轻拉试验阳性占22.97%。结论男性型脱发发病年龄偏早,发病与职业、精神神经因素有关,有家族史患者的发病年龄比无家族史患者的发病年龄更早,有家族史患者出现重型男性型脱发的可能性更大,疗效与疗程呈正相关,疗效与家族史无关,部分患者出现轻拉试验阳性。

Clinical study of androgenic alopecia in 148 patients

Objective To investigate the clinical characteristics of androgenic alopecia.Methods The clinical information of 148 cases of androgenic alopecia during the last three years was collected.The age of onset,family history,clinical classification,therapeutic efficacy,plasma dihydrotestosterone(DHT),light hair-pull test of the patients were analyzed.Results Most diseases got onset at the age between 15 and 25.Significant correlations were revealed between the family history and onset age or clinical classification(P<0.05).Elevated DHT was also revealed in 80.41% patients.The overall effective rate of fiansteride treatment and positive light hair-pull rates were 88.98% and 22.97%,respectively.Conclusion The onset age of androgenic alopecia is young.And it is correlated with occupational and psychiatric factors.Patients with family history suffer earlier onset age and higher probability of severe androgenic alopecia.However,the efficacy of treatment is correlated with the course of therapy but not with family history.