蓖麻中毒与检测方法的研究进展

目的为进一步研究蓖麻中毒性成分的快检方法及在医药领域中的应用提供参考。方法查阅近年来公开发表的论文、专著等资料,对蓖麻碱和蓖麻毒蛋白的提取检测进行概述。结果明确了蓖麻中毒性成分蓖麻碱和蓖麻毒蛋白的理化性质及提取、纯化方法,总结了这2种毒性物质的提取、分离和检测方法。结论建立快速有效的检测鉴定方法对蓖麻中毒的解救是十分必要的。

Progress in the intoxication and detection of castor

Objective To provide a reference for further research of ricinine and ricin′s rapid-detection and their application in the medical field.Methods Papers,monographs,etc.published in recent years on the extraction and detection of the ricinine and ricin were reviewed and analyzed retrospectively.Results This paper briefly reviewed the physico-chemical properties of ricinine and ricin which are the toxic factors of castor,and methods for their extraction,purification and detection.Conclusion It is quite necessary to establish a rapid and effective detection method for ricin poisoning rescue.