Adnocarcinoma of the cervix (A report of 363 cases) |
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Authors: | Ma Shaokang Lin Dongmei Sun Jianheng Huang Manni Zhang Hongtu |
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Affiliation: | (1) Department of Gynaecologic Oncology, Beijing Union Medical College, Chinese Academy of Medical Sciences, 100021 Beijing;(2) Department of PathologyCancer Hospital, Beijing Union Medical College, Chinese Academy of Medical Sciences, 100021 Beijing |
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Abstract: | From 1959 through to May, 1993, 363 patients with adenocarcinoma of uterine cervix were initially treated which accounted for 2.5% of all initially treated cases with cervical carcinoma. Patients’ mean age was 50.5 years. 46% of the cases were post-menopausal. The main symptom was irregular vaginal bleeding and/or discharge. Over 88% of the cases were in stage II and III of the disease, they were treated with radiotherapy alone. The overall 5-years survival rate was 51.8%. The recurrence rate was 17.4% with a mean time to recurrence of 33.3 months Thirteen patients recurred beyond 5 years. Recurrence was accompanied with lung metastasis in 17 patients and supraclavicular lymph node metastasis in 11. Among patients whose tumor recurred the 1- and 2-year survival rate were 35.2% and 19.2% respectively. The most significant prognostic factors were the stage of disease, the size of the tumor and the histologic subtypes. |
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Keywords: | Cervical carcinoma Radiotherapy Adenocarcinoma prognosis |
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