Synthesis, antibacterial and potential anti-HIV activity of some novel imidazole analogs |
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| Authors: | Ganguly Swastika Vithlani Vatsal Vijay Kesharwani Anup Kumar Kuhu Ritu Baskar Lakshmanan Mitramazumder Papiya Sharon Ashok Dev Abhimanyu |
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| Affiliation: | Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra Ranchi-835215, Jharkhand, India. swastikaganguly@bitmesra.ac.in |
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| Abstract: | A series of 1-(2-methyl-4-nitro-imidazol-1-yl)-3-arylaminopropan-2-ones (2a-e), 2-methyl-5-nitro-1-{2-[arylmethoxy]ethyl}-1H-imidazoles (5a-d), and N-(3-hydroxyphenyl)-2-(substituted imidazol-1-yl)alkanamides (8a-e) were synthesized with the aim to develop novel imidazole analogs with broad-spectrum chemotherapeutic properties. Title compounds were evaluated for their anti-HIV and antibacterial activities. |
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