| 欧必亭预防顺铂所致呕吐的临床研究 |
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| 引用本文： | 王蔚,刘华,郑垂志,邢雪花.欧必亭预防顺铂所致呕吐的临床研究[J].海南医学,2003,14(5):6-7. |
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| 作者姓名： | 王蔚 刘华 郑垂志 邢雪花 |
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| 作者单位： | 海南省人民医院肿瘤内科,海口,570311 |
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| 摘 要： | 目的 观察欧必亭的止吐疗效和毒性。方法 对70例接受顺铂化疗的患者,采用随机自身对照的方法,比较欧必亭和枢丹的疗效和毒性。结果 欧必亭可预防顺铂化疗所致的呕吐,疗效满意,其止吐效果与枢丹相似,两药在化疗第1—5天的止吐平均有效率分别为84.7%和82.9%,两药的疗效无统计学差异(P>0.05),但欧必亭与枢丹比较使用方便且较经济。结论 欧必亭为肿瘤化疗安全,有效的止吐药,值得临床推广。
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| 关 键 词： | 欧必亭 预防 顺铂 呕吐 疗效 毒性 |
A Clinical study of antiemetic efficacy of Navoban |
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| WANG Wei,LIU Hua,ZHENG Chui-zhi,et al..A Clinical study of antiemetic efficacy of Navoban[J].Hainan Medical Journal,2003,14(5):6-7. |
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| Authors: | WANG Wei LIU Hua ZHENG Chui-zhi |
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| Institution: | WANG Wei,LIU Hua,ZHENG Chui-zhi,et al. Medical Oncology. Hainan People's Hospital,Haikou 570311 |
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| Abstract: | Objective:To evaluate the antiemetic efficacy and toxicity of Navoban in patient receving cisplatin chemotherapy. Mettmds: A randomiged coroasover trial comparing antiemetic efficacy and toxicity of Navoban with ondansetron was peformed. Seventy patients with receving cisplantin chemotherapy were enrolled in study.The number of vomiting and nausea in one to five day was observed.Results:The average response rate of Navoban and Ondansetron in one to five day was 84.7% and 82.9% respectively; However, no significant differences was found between the two drugs(P> 0.05), efficacy of Navoban and Ondansetron were similar. Conclusion: Navoban is effective and economical anti emetic drug in controlling emesis induced by cisplatin chemotherapy. |
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| Keywords: | Navoban Ondansetron Cisplatin Emesis/Prevent and control |
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