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Impaired endocannabinoid signalling in the rostral ventromedial medulla underpins genotype-dependent hyper-responsivity to noxious stimuli
Authors:Kieran Rea  Weredeselam M. Olango  Bright N. Okine  Manish K. Madasu  Iseult C. McGuire  Kathleen Coyle  Brendan Harhen  Michelle Roche  David P. Finn
Affiliation:1. Pharmacology and Therapeutics, School of Medicine, National University of Ireland, Galway, Ireland;2. Physiology, School of Medicine, National University of Ireland, Galway, Ireland;3. NCBES Galway Neuroscience Centre and Centre for Pain Research, National University of Ireland, Galway, Ireland
Abstract:
Keywords:Pain   Affect   Wistar&ndash  Kyoto rat   Cannabinoid1 (CB1) receptor   Anandamide   Fatty acid amide hydrolase (FAAH)   Formalin   Rostroventromedial medulla (RVM)
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