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Genetic relatedness of Streptococcus pneumoniae isolates from paired blood and respiratory specimens
Authors:Harrell L J  Sharps S K  Bean R A  Reller L B
Affiliation:Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. lizzie.harrell@duke.edu
Abstract:To assess the relatedness of Streptococcus pneumoniae isolates recovered concurrently from blood and respiratory tract specimens from patients with pneumonia, we analyzed 24 paired isolates by pulsed-field gel electrophoresis (PFGE), serotyping, and antimicrobial susceptibility testing. PFGE, serotype, and/or susceptibility patterns were identical for 22 of 24 pairs. Susceptibility results for blood isolates should guide therapy.
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