实验性颈椎动力平衡失调后髓核超微结构观察

目的 探讨颈椎动平衡失调对椎间盘髓组织超微铁影响，方法 选择ＳＤ大鼠２４只，随机分为４组，手术切除大鼠颈背部浅肌群、深肌群、全肌群、建立颈椎不同程度动力平衡失调的实验模型，２、４、６个月后动态观察颈椎间盘髓组织内细胞超微结构变化，并与正常对照组相比较。结果 颈椎动力平衡失调一髓核组织内细胞退变、坏死加速加重，以全肌群损伤组最为明显，浅肌群损伤组次之，深肌群损伤组较轻。结论 颈椎动力平衡调失可加速颈

Ultrastructure of nucleus pulposus after experimental dynamic nonequilibrium of cervical spine

Objective To investigate influence of cervical dynamic nonequilibrium on ultrastructure in nucleus pulposus of cervical intervertebral disc. Methods 24 Sprague Dawley (SD) rats were divided into 4 groups randomly. The experimental model of cervical dynamic nonequilibrium of various degrees was established by means of resection of cervical shallow layer, deep layer or whole layer back muscles. After 2, 4, 6 months, the variations of ultrastructure in nucleus pulposus of cervical intervertebral disc were observed and compared with control group. Results After experimental dynamic nonequilibrium cervical intervertebrae, cells in nucleus pulposus of experimental groups degenerated and necrosed more rapidly and seriously in which the whole layer group demonstrated the most serious, the shallow layer group showed moderate and the deep layer group revealed the minor degeneration and necrosis. Conclusion Cervical dynamic nonequilibrium can accelerate the degeneration of nucleus pulposus of cervical intervertebral disc.