|
|||||
|
|
| 穿琥宁注射液中DAS-K的含量测定和贮存期的预测 | |
| 引用本文： | 王炳南,贺英菊,龙波.穿琥宁注射液中DAS-K的含量测定和贮存期的预测[J].华西药学杂志,1999,0(2):104-105. |
| 作者姓名： | 王炳南 贺英菊 龙波 |
| 作者单位： | 华西医科大学药学院，五粮液集团宜宾制药厂，华西医科大学药学院 |
| 摘 要： | 用恒温加速试验法对２％穿琥宁注射液贮存期进行预测并用紫外分光光度法在２５０ｎｍ处测定脱水穿心莲内酯琥珀酸半酯单钾盐吸光度，预测出室温下穿琥宁注射液贮存期为２．３１年。 |
| 关 键 词： | 脱水穿心莲内酯琥珀酸半酯单钾盐（DAS－K） 紫外分光光度法 稳定性 贮存期 |
PREDICTION OF THE SHELF-LIFE OF 2% CHUANHUNING INJECTION |
|
| Wang Bingnan He,Yingju Long Bo Chen Lin,Guo Lingxiao,Ding Zhiyong.PREDICTION OF THE SHELF-LIFE OF 2% CHUANHUNING INJECTION[J].West China Journal of Pharmaceutical Sciences,1999,0(2):104-105. | |
| Authors: | Wang Bingnan He Yingju Long Bo Chen Lin Guo Lingxiao Ding Zhiyong |
| Abstract: | The active principle(DAS K)2% Chuanhuning Injection is unstable. The stability of the injection was studied by classical isotermal method.Experimental results indicated that the degradation of DAS K obeys the first order kinetics. The shelf life of the injection is about 28 months at room temperature and the activation energy of the degradation is about 104.8kJ/mol. |
| Keywords: | Monopotassium salt of 14 deoxy 11 12 didehydroandro grapholide 3 19 disuccinate UV spectrophotometry Stability self life * Yibin Pharmaceutical Factory Wuliangye Group Yibin 644002 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |