超声造影在乳腺良恶性病灶鉴别诊断中的应用

目的 观察乳腺肿块实时灰阶超声造影增强模式,探讨其在乳腺良恶性病灶鉴别诊断中的价值.方法 50个乳腺肿块,恶性病灶23个,良性病灶27个,观察其超声造影增强的增强程度、增强模式,病灶边界是否清晰、消退模式,比较良恶性病变血流灌注特征.结果 50个乳腺病灶均有不同程度增强,恶性病灶表现为3级以上明显增强17个,占73.9%,呈结节状不均匀增强16个,占69.6%,增强时边界不清晰不规则,呈放射状18个,占78.3%.良性病灶27个,增强程度为3级的占40.7%（11/27）,呈整体较均匀增强20个,占74.1%,部分增强7个,占25.9%,表现为点线状、结节状或团块状增强.良恶性病灶造影增强特点的差异有统计学意义（P〈0.05）.结论 超声造影可以动态观察乳腺病灶内微血管血流灌注,提高其良恶性的鉴别诊断能力.

Application of contrast-enhanced ultrasonography in differential diagnosis of breast lesions

Objective To observe the contrast - enhanced mode of real - time gray - scale ultrasound in breast lesions, and to explore the value of real - time gray - scale ultrasound in diagnosis of breast lesions. Methods Fifty breast lesions were enrolled in this study, there were 23 malignant lesions and 27 benign lesions. Their enhanced degree, enhanced mode, lesion border, extinction mode were observed, the blood perfusion characteristics of malignant and benign lesions were compared. Results Fifty breast lesions had different degree of enhancement , and 17 malignant lesions showed significant enhancement for more than 3 grade （ 17/23, 73.9% ） , 16 lesions were inhomogeneous enhancement （ 16/23,69.6% ）, 18 lesions had unclear and irregular boundary（ 18/23, 78.3% ）. There were 27 benign lesions, most of the enhancement was less than 3 grade （20/27, 74. 1% ）, 7 lesions were partial enhancement （7/27, 25.9% ）. There was significant difference of contrast - enhanced features between the two groups （ P 〈 0.05 ）. Conclusion Real - time gray - scale contrast - enhanced ultrasound can dynamically observe the microvessel blood perfusion of breast lesions, it can improve the diagnosis level.