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Change ofCoagulation Factor Ⅷ and Antithrombin Ⅲ Activity in Bank-Stored Blood
引用本文:胡丽华,余忠清,张清. Change ofCoagulation Factor Ⅷ and Antithrombin Ⅲ Activity in Bank-Stored Blood[J]. 华中科技大学学报(医学英德文版), 2000, 20(3): 263-264. DOI: 10.1007/BF02887009
作者姓名:胡丽华  余忠清  张清
作者单位:HU Lihua,YU Zhongqin,ZHANG Qing Blood Transfusion Department,Xiehe Hospital,Tongji Medical University,Wuhan 430022
摘    要:Blood storage and blood transfusion have beenimportantclinical work.In recentyears,the demandfor the quality of blood transfusion is getting higher.Great progress has been made in blood storage tech-nique and more and more reports on change in bloodcomponents during storage have been published.However,reports on dynamic changes in blood com-ponentsin bank- stored blood are stillrare.The paperinvestigated the dynamic change of blood componentsF :c and AT- in blood stored in blood bank un-der…

关 键 词:blood storage  antithrombin Ⅲ  coagulation factor Ⅷ  
收稿时间:2000-05-29

Change of coagulation factor VIII and antithrombin III activity in bank-stored blood
Hu Lihua,Yu Zhongqin,Zhang Qing. Change of coagulation factor VIII and antithrombin III activity in bank-stored blood[J]. Journal of Huazhong University of Science and Technology. Medical sciences, 2000, 20(3): 263-264. DOI: 10.1007/BF02887009
Authors:Hu Lihua  Yu Zhongqin  Zhang Qing
Affiliation:Blood Transfusion Department, Xiehe Hospital, Tongji Medical University, Wuhan 430022
Abstract:Summary Coagulation factor VIII and antithrombin III activity were detected in 15 health donors. It was found that antithrombin III activity decreased obviously 12 h after blood drawing. It lost 56 % of the activity at the 3rd day, and 70 % of the activity at the 7th day. FVIII:c showed no obvious change after 24 h, until the 3rd day. It lost 40 % – 60 % of the activity after 36 h and was reduced to the 30 % of the original activity at the 5th day. Our results suggested that at the 3rd day coagulation factor VIII of bank-stored blood can be used to replenish antithrombin III, while bank-stored blood in one day can be used to replenish FVIII.
Keywords:blood storage  antithrombin- III  coagulation factor VIII
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