| 绝经后2型糖尿病患者的骨密度变化及其相关性研究 |
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| 引用本文： | 周强,刘炳炜,干正琦,王宏智,俞歌. 绝经后2型糖尿病患者的骨密度变化及其相关性研究[J]. 实用全科医学, 2010, 8(1): 32-33 |
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| 作者姓名： | 周强 刘炳炜 干正琦 王宏智 俞歌 |
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| 作者单位： | [1]浙江省嘉兴市第一医院内分泌科,314000 [2]浙江省杭州市第一医院ICU,314000 |
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| 摘 要： | 目的探究女性2型糖尿病患者绝经后的骨密度变化及其与糖尿病的相关性。方法对76例绝经后女性2型糖尿病患者及80例健康的绝经女性用双能X射线吸收法行L2-4、Ward’s三角区、股骨颈、大转子骨密度测量，并测定糖尿病患者空腹血糖、空腹胰岛素、空腹C肽、糖基化血红蛋白等指标。结果①绝经后女性2型糖尿病患者L4、Ward’s三角区骨密度均较健康者显著降低（P〈0．05）。②多元回归分析显示：女性糖尿病患者骨密度改变与糖尿病病程、糖基化血红蛋白及绝经年数是负相关（P〈0．05），与体重指数呈正相关（P〈0．05），与空腹血糖、胰岛素及C-肽等未见相关性。结论2型糖尿病女性患者绝经后骨密度降低较健康女性更为明显。糖尿病的病程和长期的高血糖对骨密度降低有一定作用。
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| 关 键 词： | 2型糖尿病 骨密度 绝经女性 |
The Change of Bone Mineral Density in Postmenopausal Women with Type 2 Diabetes Mellitus and its Correlative Study |
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| ZHOU Qiang,LIU Bing-wei,GAN Zheng-qi,et al.. The Change of Bone Mineral Density in Postmenopausal Women with Type 2 Diabetes Mellitus and its Correlative Study[J]. Applied Journal Of General Practice, 2010, 8(1): 32-33 |
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| Authors: | ZHOU Qiang LIU Bing-wei GAN Zheng-qi et al. |
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| Affiliation: | ZHOU Qiang,LIU Bing-wei,GAN Zheng-qi,et al.Department of Endocrinology,the First Hospital of Jiaxing,Jiaxing 314000,Zhejiang,China |
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| Abstract: | Objective To study the changes of bone mineral density(BMD) in postmenopausal women with type 2 diabetes mellitus and the possible factors involved in.Methods 76 cases of female patients with type 2 diabetes and 80 healthy women received determination of bone mineral density of lumbar spines(L2-4),femoral neck,Ward's triangle,and trochanter by Dual energy X-ray absorptiometry.Fasting blood glucose(FPG),fasting insulin,fasting C-peptide,HbA1c of diabetic patient were tested.Results Compared with normal group... |
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| Keywords: | Type 2 diabetes mellitus Bone mineral density Postmenopausal women |
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