频域相干光断层扫描观察特发性黄斑裂孔患者手术前后光感受器细胞层改变

目的 探讨特发性黄斑裂孔患者手术前后光感受器细胞层内外节的改变特征.方法 回顾性病例系列研究.收集32例(32只眼)确诊并接受手术治疗的特发性黄斑裂孔患者的临床资料进行回顾性分析,同时对其手术前后的高分辨率频域相干光断层扫描(OCT)图像进行对比研究.患者手术前与后logMAR视力和光感受器细胞层内外节被破坏区域直径比...

Recovery of photoreceptor inner/outer segment junction in spectral domain optical coherence tomography after surgery in idiopathic macular hole

Objective To evaluate the findings of spectral domain optical coherence tomography (SD-OCT) in patients with idiopathic macular hole (IMH). Methods It was a retrospective case series study. Pre- and post-operative data from patients with IMH during 14 months were analyzed retrospectively. The main outcome data included logarithm of the minimal angle of resolution (logMAR) and SD-OCT findings, including the size of the IMH and the disruption of the boundary line between inner segments (IS) and outer segments (OS) of the photoreceptors. The data were analyzed using the statistical software SPSS14.0. The correlation among various data was analyzed by Bivariate correlation. The pre-and post-operative data were compared by paired-samples t-tests. Results Thirty two eyes of 32 patients were studied. The mean logMAR was 1.16±0.46 (ranged from 0.40 to 2.00), the mean diameter of macular hole was (859.7±292.0) μm (ranged from 332 to 1568 μm).The mean diameter of IS/OS disruption was (1965.1±584.1) μm (ranged from 867 to 3444 μm). In eyes after surgery, the mean logMAR was 0.89±0.46 (ranged from 0.30 to 2.00), the mean diameter of the IS/OS disruption was (1350.4±642.6) μm (ranged from 153 to 2546 μm), both were decreased significantly as compare with the preoperative data(t=3.384,6.360;P<0.05). Preoperative diameter of macular hole(r=0.583) and IS/OS disruption(r=0.416) were correlated significantly with postoperative logMAR(P<0.05). Conclusions Preoperative diameter of macular hole and IS/OS disruption play the main role in vision prognosis. The IS/OS disruption is decreased significantly after the operation.