| 单核细胞趋化蛋白-1与缺血性卒中 |
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| 引用本文： | 宋丽云,王荔. 单核细胞趋化蛋白-1与缺血性卒中[J]. 国际脑血管病杂志, 2009, 17(12). DOI: 10.3760/cma.j.issn.1673-4165.2009.12.012 |
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| 作者姓名： | 宋丽云 王荔 |
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| 作者单位： | 山西医科人学第二医院神经内科,太原,030001;山西医科人学第二医院神经内科,太原,030001 |
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| 基金项目： | 山西省高校科技研究开发项目 |
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| 摘 要： | 炎症反应在缺血性卒中的发生和发展过程中起着重要作用.单核细胞趋化蛋白-1(monocyte chemotactic protein-1,MCP-1)是趋化因子CC类哑家族成员之一,可趋化和激活单核细胞、T细胞等多种细胞,促进细胞因子表达,参与缺血性脑损伤的发生.文章对MCP-1与缺血性卒中相关的研究进展做了综述.
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| 关 键 词： | 趋化因子CCL2 动脉粥样硬化 卒中 炎症 |
Monocyte chemotactic protein-1 and ischemic stroke |
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| SONG Li-yun,WANG Li. Monocyte chemotactic protein-1 and ischemic stroke[J]. International Journal of Cerebrovascular Diseases, 2009, 17(12). DOI: 10.3760/cma.j.issn.1673-4165.2009.12.012 |
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| Authors: | SONG Li-yun WANG Li |
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| Abstract: | Inflammatory reaction plays an important role in the occurrence and development of ischemic stroke. Monocyte chemotactic protein-1 (MCP-1) is one of the subfamily members of the CC chemokine class. It can attract and activate a variety of cells, such as monocytes and T lymphocytes, promote the expression of cytokines, and participate in the occurrence of ischemic brain injury. This article reviews the progresses on the MCP-1 and ischemic stroke-related research. |
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| Keywords: | chemokine CCL2 atherosclerosis stroke inflammation |
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