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Diabetes mellitus aggravates ranolazine-induced ECG changes in rats
Authors:Mashayekhi-Sardoo  Habibeh  Mohammadpour  Amir Hooshang  Mehri   Soghra  Kamali   Hossein  Sahebkar   Amirhossein  Imenshahidi   Mohsen
Affiliation:1.Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
;2.Department of Clinical Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
;3.Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
;4.Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
;5.Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
;6.Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
;7.Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
;8.School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
;
Abstract:Journal of Interventional Cardiac Electrophysiology - Diabetes mellitus (DM) is known to affect the pharmacokinetics of drugs. In this study, we evaluated the effect of DM on the liver content of...
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