不同方式治疗小儿急性感染性喉炎的临床疗效分析

目的 对比布地奈德雾化吸入、地塞米松雾化吸入和地塞米松静脉注射治疗小儿急性感染性喉炎的疗效.方法 将96例小儿急性喉炎患者完全随机分为观察组、对照1组和对照2组,各32例.观察组使用布地奈德雾化吸入治疗.对照1组采用传统方法地塞米松雾化吸入治疗.对照2组应用地塞米松静脉注射治疗.治疗后第3天比较3种治疗方法的效果.结果 观察组、对照1组及对照2组的治疗有效率分别为96.9％ (31/32)、71.9％ (23/32)、93.8％(30/32).观察组治疗总有效率明显高于对照1组(P＜0.05).观察组患儿犬吠样咳、声嘶、喉鸣、吸气性呼吸困难症状的消失时间均明显短于对照1组(2.6±1.3)d比(3.5±1.4)d,(3.8±1.2)d比(4.5±2.7)d,(1.92±0.24)d比(2.81±1.26)d,(1.8±0.6)d比(2.6±0.8)d],2组间差异均有统计学意义(均P＜0.05).结论 布地奈德雾化吸入治疗急性喉炎,疗效优于传统地塞米松雾化吸入,可以替代地塞米松静脉注射治疗,起效迅速,应用方便,安全可靠.

Analysis of the effect of different methods on acute infectious laryngitis in children

Objective To compare the effect of three methods of inhalation of budesonide suspension,inhalation of dexamethasone and injection of dexamethasone in treatment of acute infectious laryngitis in children.Methods Totally 96 children with acute infectious laryngitis were randomly divided into three groups.32 cases in the observation group were treated with inhalation of budesonide suspension,32 cases in control group 1 were treated with inhalation of dexamethasone,32 cases in control group 2 were treated with injection of dexamethasone.The therapetic effect was compared on the 3th day after treatment.Results The total effective rate of the observation group,control group 1 and control group 2 was 96.9% （31/32）,71.9% （23/32）,93.8% （30/32）.The healing rate in the observation group was obviously higher than that in control group !,the difference was significantly detected between the two groups （P 〈 0.05）.The time of hoarseness,barking cough,dyspea and laryngeal stridor symptoms disappeared in the observation group was obviously shorter than in the control group 1 （2.6 ± 1.3） d vs （3.5±1.4）d,（3.8±1.2）dvs （4.5±2.7）d,（1.92±0.24）dvs （2.81±1.26）d,（1.8±0.6）dvs（2.6± 0.8） d],the significant difference was detected between the two groups （P 〈 0.05）.Conclusions The effect of budesonide inhalation is better than that of dexamethasone inhalation.Budesonide inhalation is worth to be applied in clinic,rapid onset,convenient,safe and reliable.Budesonide inhalation can replace injection of dexamethasone.