儿童弥漫性轴索损伤的临床特征及治疗(附26例报告)

目的探讨儿童弥漫性轴索损伤(Diffuse axonal injury,DAI)的发病机制、临床特征及治疗方法。方法回顾性分析本院于2008年7月至2014年1月收治的26例儿童弥漫性轴索损伤病例的临床诊疗经过,并随访其预后。结果 26例中,死亡3例,植物生存1例,5例出现不同程度后遗症,基本痊愈17例。结论儿童弥漫性轴索损伤受伤原因与成人不同,以高坠伤多见,病死率及致残率较成人低,早期诊断、积极治疗预后良好。

The traits and therapy of diffuse axonal injury in children:a review of 26 cases

Objetive To explore the pathogenesis,traits and therapeutic methods in children who sub-jected to diffuse axonal injury(DAI).Methods Twenty-six children with DAI from July 2008 to January 2014 were retrospectively analysised and followed up.The process of diagnosis,therapeutic methods and prognosis were recorded.Results 17 children were cured basically.3 cases were dead and 1 vegetative state,5 had dif-ferent extent complications. Conclutions The causes of DAI in children are different from adults,the most common factor is high-falling injury,whereas the children DAI have a better fatality rate,the early diagnosis and active treatment may lead to a good result.