| 复方壬苯醇醚-9栓对家兔抗生育作用和阴道刺激性实验研究 |
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| 引用本文： | 张颖,陈坚,侯庆昌,邵长凤. 复方壬苯醇醚-9栓对家兔抗生育作用和阴道刺激性实验研究[J]. 中国计划生育学杂志, 2006, 14(5): 287-288 |
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| 作者姓名： | 张颖 陈坚 侯庆昌 邵长凤 |
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| 作者单位： | 天津市计划生育研究所,300191 |
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| 摘 要： | 目的:观察复方壬苯醇醚-9栓对家兔的抗生育作用和阴道刺激性。方法:采用改良Eckstein方法,对性成熟雌性家兔进行阴道刺激性研究。结果:家兔抗生育实验结果表明,高、中、低剂量实验药物组的避孕率分别为 100％、80％和60％;阴道刺激炎症总分值分别为4．3、3．5、3．0。结论:在实验应用剂量下壬苯醇醚-9抗生育作用及对阴道刺激性在可接受范围内。
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| 关 键 词： | 复方壬苯醇醚-9 抗生育作用 阴道刺激性 动物实验 |
| 收稿时间： | 2005-12-16 |
| 修稿时间： | 2006-03-21 |
Effect of Nonoxynol - 9 Compound on Antifertility and Vaginal Irritation in Rabbits |
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| Zhang Ying, Chen Jian, Hou Qingchang,et al.. Effect of Nonoxynol - 9 Compound on Antifertility and Vaginal Irritation in Rabbits[J]. Chinese Journal of Family Planning, 2006, 14(5): 287-288 |
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| Authors: | Zhang Ying Chen Jian Hou Qingchang et al. |
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| Affiliation: | Tianjin Research Institute of Family Planning, Tianjin 300191 |
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| Abstract: | Objective: To observe effect of Nonoxynol - 9 compound suppository on antifertility and vaginal irritation in the rabbits. Methods: Female mature rabbits were taken an experimentation on vaginal irritation by the method of improved Eckstein. Results: Contraceptive rate in high, middle and low dose groups was 100% , 80% , 60% , respectively. Vaginal irritation score in three groups were4.3, 3.5, 3.0, respectively. Conclusion: Nonoxynol-9 compound suppository is antifertility and its irritation in the rabbit is acceptable. |
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| Keywords: | Nonoxynol - 9 compound suppository Antifertility Vaginal irritation Experimentation on animals |
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