| 喉疾灵口含片抗炎抑菌作用实验研究△ |
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| 引用本文： | 赵永良,王超,韩亚朋,刘景彬,刘红玲,谢印芝,程鹏,李建慧.喉疾灵口含片抗炎抑菌作用实验研究△[J].中国现代中药,2011,13(4):44-47. |
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| 作者姓名： | 赵永良 王超 韩亚朋 刘景彬 刘红玲 谢印芝 程鹏 李建慧 |
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| 作者单位： | 天津美伦医药集团有限公司药物研究院,天津,300400 |
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| 基金项目： | 天津市科技创新专项基金项目 |
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| 摘 要： | 目的:对喉疾灵口含片进行抗炎、抑菌作用实验研究。方法:采用二甲苯致小鼠耳壳肿胀、角叉菜致大鼠足趾肿胀、大鼠棉球肉芽肿等炎症模型,以及含药血清体外抑菌实验模型,评价喉疾灵口含片的抗炎、抑菌作用。结果:与空白对照比较,喉疾灵口含片明显抑制了小鼠耳壳肿胀(P<0.05或P<0.01)、大鼠足趾肿胀以及大鼠棉球肉芽肿的形成(P<0.05);其含药血清对金黄色葡萄球菌、铜绿假单胞菌及白色念珠菌具有明显的抑制作用(P<0.05或P<0.01)。结论:上述结果表明,喉疾灵口含片对化学刺激所致炎症有明显的抑制作用,其含药血清具有显著的体外抑菌作用。
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| 关 键 词： | 喉疾灵口含片 胶囊 抗炎 抑菌 |
| 收稿时间： | 2010/9/20 0:00:00 |
Experimental Study on the Anti-inflammatory and Antibacterial Effects of Houjiling Buccal Tablet |
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| ZHAO Yong-liang,WANG Chao,HAN Ya-peng,LIU Jing-bin,LIU Hong-ling,XIE Yin-zhi,CHENG Peng and LI Jian-hui.Experimental Study on the Anti-inflammatory and Antibacterial Effects of Houjiling Buccal Tablet[J].Modern Chinese Medicine,2011,13(4):44-47. |
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| Authors: | ZHAO Yong-liang WANG Chao HAN Ya-peng LIU Jing-bin LIU Hong-ling XIE Yin-zhi CHENG Peng and LI Jian-hui |
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| Institution: | ZHAO Yong-liang,WANG Chao,HAN Ya-peng,LIU Jing-bin,LIU Hong-ling,XIE Yin-zhi,CHENG Peng,LI Jian-hui(Institute of Materia Medica,Tianjin Meilun Pharmaceutical Group Inc,Tianjin 300400,China) |
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| Abstract: | Objective: To study the anti-inflammatory and antibacterial effects of Houjiling buccal tablet(HJLBT)by experiments.Methods: Three inflammatory models including the swelling of ear induced by xylene in mice,carrageenan-induced foot acute inflammatory edema in rat,and the cotton-pellet granuloma of the rat were employed to evaluate the anti-inflammatory effects of the drug.Additionally,the model of bacteriostasis in vitro by the serum with drug was used to examine the antibacterial activities of HJLBT.Result... |
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| Keywords: | Houjiling buccal tablet Capsule Anti-inflammation Bacteriostasis |
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