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乳腺癌患者血清胰岛素样生长因子-1术前及术后水平检测意义研究
引用本文:刘小青,李玉,徐光辉. 乳腺癌患者血清胰岛素样生长因子-1术前及术后水平检测意义研究[J]. 中国实用医药, 2011, 6(19): 11-12
作者姓名:刘小青  李玉  徐光辉
作者单位:江苏省连云港市第一人民医院肿瘤内科,222000
摘    要:目的 检测乳腺癌患者术前及术后血清胰岛素样生长因子-1的水平.方法 应用双位点免疫放射测定法(IRMA)对不同TNM分期的49例乳腺癌患者术前、术后外周血中IGF-1水平进行检测,20例健康志愿者设为正常对照.结果 乳腺癌患者手术前后血清IGF-1水平均高于正常对照(P<0.05),手术前后乳腺癌患者血清IGF-1水平差异无统计学意义(P>0.05).结论 乳腺癌患者血清IGF-1参与乳腺癌的发病过程,是乳腺癌发生、发展过程中的重要因子.

关 键 词:胰岛素样生长因子-1  乳腺癌  检测

Significance of detection the levels of insulin-like growth factor-1 in peripheral blood with breast cancer before and after operation
LIU Xiao-Qing,LI Yu,XU Guang-hui. Significance of detection the levels of insulin-like growth factor-1 in peripheral blood with breast cancer before and after operation[J]. China Practical Medical, 2011, 6(19): 11-12
Authors:LIU Xiao-Qing  LI Yu  XU Guang-hui
Affiliation:, et al. Department of Medical Oncology,The First people’s Hospital of Lianyungang City,Lianyun gang,222000,China
Abstract:Objective To detect the serum insulin-like growth factor-1(IGF-1)levels in patients with breast cancer before and after operation and explore the feasibility of its clinical significance. Methods Immunoradiometric assay(IRMA)was used to detect the IGF-1 level in peripheral blood in 49 pre-and post-operative patients with breast cancer(based on TNM staging).20 healthy subjects were taken as control group. Results The serum IGF-1 levels of pre-and post-operative patients with breast cancer were higher than th...
Keywords:Insulin-like growth factor-1  Breast cancer  Detection  
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