Susceptibilities of Candida Species Isolated from the Lower Gastrointestinal Tracts of High-Risk Patients to the New Semisynthetic Echinocandin LY303366 and Other Antifungal Agents |
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| Authors: | George G Zhanel James A Karlowsky Sheryl A Zelenitsky Michael A Turik and Daryl J Hoban |
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| Institution: | Department of Medical Microbiology1. and Faculty of Pharmacy,2. University of Manitoba, and Departments of Clinical Microbiology3. and Medicine,4. Health Sciences Centre, Winnipeg, Manitoba, Canada, and Lilly Research Laboratories, Indianapolis, Indiana5. |
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| Abstract: | Fifty-two percent of stool specimens collected from 1,200 high-risk patients were colonized with yeasts, primarily Candida albicans (53.6%) and Candida glabrata (35.7%). Susceptibilities to all antifungal agents tested, including LY303366, were similar to those reported previously for Candida species isolated from blood. |
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