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复方鱼腥草口服制剂治疗儿童呼吸道感染有效性Meta分析
引用本文:张亮,吕丽丽,王建方,石芮凡,吴旦,胡江宁.复方鱼腥草口服制剂治疗儿童呼吸道感染有效性Meta分析[J].中草药,2020,51(20):5279-5286.
作者姓名:张亮  吕丽丽  王建方  石芮凡  吴旦  胡江宁
作者单位:浙江康恩贝制药股份有限公司, 浙江杭州 310052;浙江省中药制药技术重点实验室, 浙江杭州 310052
基金项目:中药潜力品种的技术升级研究(2013C03005)
摘    要:目的系统评价复方鱼腥草口服制剂治疗儿童呼吸道感染的临床有效性,为其临床应用提供依据。方法检索数据库,查找复方鱼腥草口服制剂治疗儿童呼吸道感染的临床对照试验文献,通过评价文献质量及对文献数据进行Meta分析,评价复方鱼腥草口服制剂的有效性。结果共纳入文献17篇,其中临床随机对照试验(RCT)文献15篇。文献平均得分为4分。纳入文献中共收录患者1 766例,采用复方鱼腥草口服制剂对比单纯对照组总有效率更高,安全性好,差异具有统计学意义。结论复方鱼腥草口服制剂对治疗儿童呼吸道感染具有很好的疗效和安全性。

关 键 词:复方鱼腥草口服制剂  呼吸道感染  有效性  Meta分析  安全性
收稿时间:2020/5/25 0:00:00

Meta analysis of efficacy of Compound Yuxingcao Oral Preparation in treatment of respiratory diseases in children
ZHANG Liang,LV Li-li,WANG Jian-fang,SHi Rui-fan,WU Dan,HU Jiang-ning.Meta analysis of efficacy of Compound Yuxingcao Oral Preparation in treatment of respiratory diseases in children[J].Chinese Traditional and Herbal Drugs,2020,51(20):5279-5286.
Authors:ZHANG Liang  LV Li-li  WANG Jian-fang  SHi Rui-fan  WU Dan  HU Jiang-ning
Institution:Zhejiang CONBA Pharmaceutical Co., Ltd., Hangzhou 310052, China;Zhejiang Key Laboratory of Traditional Chinese Medicine Pharmaceutical Technology, Hangzhou 310052, China
Abstract:Objective To systematically evaluate the clinical efficacy of Compound Yuxingcao Oral Preparation in the treatment of respiratory diseases in children, and provide basis for its clinical application. Methods The clinical controlled trial literatures of Compound Yuxingcao Oral Preparation in the treatment of respiratory diseases in children were searched from database to evaluate the effectiveness of Compound Yuxingcao Oral Preparation by evaluating the quality of literatures based on Meta-analysis. Results A total of 17 literatures were included, of which 15 were RCT literatures. The average score of literatures was 4. A total of 1766 patients were included in the included literatures. The total effective rate and safety of Compound Yuxingcao Oral Preparation were higher than that of the control group, and the difference was statistically significant. Conclusion Compound Yuxingcao Oral Preparation has good efficacy and safety in the treatment of children with respiratory tract infection.
Keywords:Compound Yuxingcao Oral Preparation  respiratory diseases  effectiveness  Meta analysis  safety
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