红花黄色素类化合物的药代动力学研究进展

红花黄色素类化合物是红花的重要活性成分,具有抗炎、抗氧化、神经保护等药理活性。本文通过对红花黄色素类化合物的药代动力学研究进行综述，总结其吸收、分布、代谢、排泄过程，探讨中药复方中该类化合物的代谢过程及规律，为红花及其制剂的药效物质及作用机制研究提供参考。此外，由于红花黄色素类化合物在体内吸收差、生物利用度低，本文同时关注了提高红花黄色素类生物利用度的相关研究，以期为中药新药的研发提供新的思路。

Research Progress of the Pharmacokinetics of Safflor Yellow Pigments

Safflor yellow pigments are important active components of Carthamus tinctorius L, which exhibit activities including anti-inflammation, antioxidation, neuroprotection and so on. This review makes a brief summary of the absorption, distribution, metabolism and excretion processes of safflor yellow pigments, including their metabolic processes and patterns. In addition, because of their poor absorption and low bioavailability in vivo, this paper also pays attention to the researches on improving the bioavailability of safflor yellow pigments.