The reduction of excitability of the γ-loop by 1,3-dimethyl-5-aminoadamantane (DMAA)

Summary The -loop of pretibial flexor muscles was investigated before and after i.v. injection of 10 mg/kg DMAA in precollicular and prenigral decerebrate cats. DMMA reduces significantly the reflex discharge rate of Ia muscle spindle afferents, a result which might be important in regard of a hyperactive -motor system.Supported by the Deutsche Forschungsgemeinschaft, SFB 33.