| 横纹肌肉瘤(RMS)DNA倍体与临床病理关系的研究 |
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| 引用本文： | 陈炳旭,赖日权,李小敏,冯晓冬,谢宇晖. 横纹肌肉瘤(RMS)DNA倍体与临床病理关系的研究[J]. 中国体视学与图像分析, 1997, 0(2) |
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| 作者姓名： | 陈炳旭 赖日权 李小敏 冯晓冬 谢宇晖 |
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| 作者单位： | 广州军区广州总医院，广州市亿鸣科技发展有限公司 |
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| 摘 要： | 本文应用ＥＭＡＩＬ－１００病理图像分析仪（ｉｍａｇｅ－ａｎａｌｙｓｉｓ，ＩＡ）对ＲＭＳ瘤细胞的ＤＮＡ倍体含量进行测试，以揭示ＤＮＡ倍体含量与ＲＭＳ的诊断、组织类型、分级、ＰＣＮＡ表达强度及预后的关系。通过对确诊的４３例ＲＭＳ进行测试，发现所有患者的瘤细胞ＤＮＡ异倍体含量（包括多倍体和非整倍体）显著高于其二倍体含量，而在ＲＭＳ各组织分级、ＰＣＮＡ表达强度（尽管它们与ＤＮＡ异倍体含量呈正相关）及类型之间瘤细胞的ＤＮＡ倍体分布并无显著性差异（ｂＲＭＳ除外）。说明ＤＮＡ倍体含量在ＲＭＳ的诊断上有参考价值，而对其组织类型、分级、ＰＣＮＡ表达强度及预后意义不大。
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| 关 键 词： | RMS；图象分析；DNA倍体含量；PCNA |
The study of clinical pathology and DNA ploidy in rhabdomyosarcoma (RMS) |
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| Chen Bingxu,Lai Riquan,Li Xiaomin et al. The study of clinical pathology and DNA ploidy in rhabdomyosarcoma (RMS)[J]. Chinese Journal of Stereology and Image Analysis, 1997, 0(2) |
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| Authors: | Chen Bingxu Lai Riquan Li Xiaomin et al |
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| Abstract: | In order to reveal the relationship of RMS tumor cells DNA ploidy content which was measured by EMAIL-100 pathology image analyser to its diagnosis, tissue typing, grading, PCNA express degree and prognosis, 43 confirmed RMS patients were randomly selected in this study. The results showed that the polyploidy content was significantly higher than diploid content in all RMS patients, but there wasnt signficant difference among grades, PCNA express degrees and DNA ploidy distribution in tissue types of RMS. It indicates that the DNA ploidy content play a role in the diagnosis, but there is no remarkable sense to tissue typing, grading, PCNA express degree and prognosis of RMS. |
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| Keywords: | RMS image analysis DNA ploidy content PCNA |
| 本文献已被 CNKI 等数据库收录！ |
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