Inhibition of cryptosporidium parvum in vitro by 9-(alkylthio)acridine derivatives |
| |
| Authors: | Khalifa L Rosales M J Mascaro C Karolak-Wojciechowska J Bsiri N Brouant P Barbe J |
| |
| Affiliation: | Institute of Biotechnology, Faculty of Science, University of Granada, Spain. |
| |
| Abstract: | The synthesis of several acridinic thioethers is described. Compounds prepared were tested in vitro as potential drugs against the opportunistic infection known as cryptosporidiosis. With a view to predict activity, the quantitative structure-activity relationships were investigated. Correlations between experimental data and either log P or pKa are discussed. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
