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A comparison of plasma and serum levels of two tricyclic antidepressants: Imipramine and desipramine
Authors:Joseph J. Saady  Valerie L. Bloom  N. Narasimhachari  Solomon C. Goldberg  Robert O. Friedel
Affiliation:(1) Department of Pathology, Medical College of Virginia, MCV Station, Box 597, 23298 Richmond, Virginia, USA;(2) Department of Psychiatry, Medical College of Virginia, MCV Station, Box 597, 23298 Richmond, Virginia, USA
Abstract:This study was performed to determine the difference, if any, between serum and plasma levels of the tricyclic antidepressant drugs imipramine and desipramine. Serum and plasma samples were drawn simultaneously from patients taking either of these drugs. Statistical analysis indicated no difference in the drug levels; that is, serum and plasma levels were identical.
Keywords:Imipramine  Desipramine  Serum  Plasma  Correlation
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