温针灸治疗膝关节骨性关节炎：随机对照研究

目的:探讨治疗膝关节骨性关节炎安全、有效的治疗方案.方法:将90例患者随机分为温针灸组、西药组、等待组,每组30例.温针灸组采用温针疗法,穴取血海、内膝眼、犊鼻、足三里等;西药组口服布洛芬缓释胶囊;等待组不采取任何治疗.运用患者"膝关节骨性关节炎自评量表"(WOMAC)及中文版"简明健康状况调查表"(SF-36)在治疗前、治疗2周后、治疗后10周随访时进行疗效评估.结果:治疗2周后温针灸组总有效率为86.7%、西药组90.0%优于等待组的60.0%(P<0.05),温针灸组与西药组疗效差异无统计学意义(P>0.05);随访时温针灸组总有效率为83.3%优于西药组的60.0%(P<0.05).温针灸组与西药组治疗后WOMAC和SF-36评分比较差异均无统计学意义(均P>0.05),随访时温针灸组WOMAC和SF-36评分改善优于西药组(P<0.01,P<0.05).结论:温针灸治疗膝关节骨性关节炎近期疗效与口服西药布洛芬相当,远期疗效优于布洛芬.

A randomized controlled study on warming needle moxibustion for treatment of knee osteoarthritis

Objective To assess the short-term and long-term therapeutic effect of warming needle moxibustion for treatment of knee osteoarthritis. Methods Ninety cases were randomly divided into a warming needle moxibustion group, a western medicine group and a waiting group, 30 cases in each group. The warming needle moxibustion group was treated with warming needle moxibustion on Xuehai (SP 10), Dubi (ST 35) and Zilsanli (ST 36), etc.; the western medicine group was treated with oral administration of Ibuprofen sustained release capsule; the waiting group did not receive any treatment. Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and Chinese version of SF-16 were used to assess the therapeutic effect before treatment, after treatment and 10 weeks after treatment. Results After treatment for 2 weeks, the total effective rate was 86. 7% in the warming needle moxibustion group, 90. 0% in the western medicine group, and 60. 0% in the waiting group, both the warming needle moxibustion group and the western medicine group being significantly better than the waiting group (both P<0. 05) and with no significant difference between the warming needle moxibustion group and the western medicine group (P>0. 05); 10 weeks after treatment, the total effective rate of 83. 3% in the warming needle moxibustion group was better than that of 60. 0% in the western medicine group (P<0. 05). There were no significant differences in comparison of WOMAC and SF-16 scores after treatment between the warming needle moxibustion group and the western medicine group, and the warming needle moxibustion group in improvement of these scores was superior to the western medicine group (P<0. 01,P<0. 05). Conclusion The therapy of warming needle moxibustion is effective for treatment of knee osteoarthritis, and the short-term therapeutic effect is same as that of oral administration of Ibuprofen and the long-term therapeutic effect is better than that of Ibuprofen.