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VBI性眩晕患者血浆内皮素水平与血液流变相关性研究
引用本文:卢丹,孙伟. VBI性眩晕患者血浆内皮素水平与血液流变相关性研究[J]. 重庆医学, 2009, 38(6)
作者姓名:卢丹  孙伟
作者单位:重庆市中医研究院中心实验室,400013;重庆市中医研究院检验科,400013
基金项目:重庆市卫生局中医药科研项目 
摘    要:目的 研究椎-基底动脉供血不足(VBI)眩晕患者血浆内皮素(endothelin,ET)水平与血液流变性(hemorheology),探讨其生化及血液流变因素在眩晕发病中的作用.方法 观察50例VBI眩晕患者血浆ET含量及血液流变性并与对照组比较.结果 VBI眩晕患者血浆ET、全血高切黏度、低切黏度、红细胞聚集指数、红细胞刚性指数、红细胞变形指数、血浆纤维蛋白原含量高,与对照组比较差异有统计学意义(P<0.05).结论 血浆ET升高与血液高黏滞状态存在相关性,在VBI眩晕发病机制中起一定的作用.

关 键 词:VBI眩晕  内皮素  血液流变学

Relation study between endothelin and hemorheology in patients with vertebrobasilar insufficiency veritigo
LU Dan,SUN Wei. Relation study between endothelin and hemorheology in patients with vertebrobasilar insufficiency veritigo[J]. Chongqing Medical Journal, 2009, 38(6)
Authors:LU Dan  SUN Wei
Affiliation:LU Dan1,SUN Wei2(1.Central Laboratory,2.Department of Clinical Laboratory,Chongqing Academy of Traditional Chinese Medicine,Chongqing 400013,China)
Abstract:Objective To analyze the correlation between the expression of endothelin(ET) in the plasma and the hemorheology in vertebrobasilar insufficiency(VBI) veritigo,and to discuss the role of these biochemical and hemorheological factors in the development of veriligo.Methods To analyze the expression level of plasma endothelin and the hemorheology in 50 patients and compare it with control group.Results The ET level,blood viscosity of high and low shear stress,RBC aggregation index,RBC stiffness index,RBC trans...
Keywords:vertebrobasilar insufficiency veritigo  endothelin  hemorheology  
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