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全反式维A酸治疗急性早幼粒细胞白血病出现阴囊溃疡2例
引用本文:朱铁山,俞宝田,段明辉,刘继海,范静波. 全反式维A酸治疗急性早幼粒细胞白血病出现阴囊溃疡2例[J]. 临床皮肤科杂志, 2003, 32(10): 612-613
作者姓名:朱铁山  俞宝田  段明辉  刘继海  范静波
作者单位:中国医学科学院、中国协和医科大学北京协和医院皮肤科,北京,100730;中国医学科学院、中国协和医科大学北京协和医院内科,北京,100730
摘    要:报告2例急性早幼粒细胞白血病患者在应用全反式维A酸治疗后出现阴囊溃疡。2例均为男性,例1 38岁,例2 39岁,因急性早幼粒细胞白血病给予全反式维A酸治疗,分别在治疗19d和10d后出现阴囊溃疡。2例患者的溃疡均在停用全反式维A酸、加强患处换药后愈合。

关 键 词:急性早幼粒细胞白血病  全反式维A酸  阴囊溃疡  不良反应
文章编号:1000-4963(2003)10-0612-02
修稿时间:2002-12-25

The treatment of acute promyelocytic leukemia with all-trans retinoic acid resulting in scrotal ulceration:a report of 2 cases
ZHU Tie-shan,YU Bao-tian,DUAN Ming-hui,LIU Ji-hai,FAN Jing-bo. The treatment of acute promyelocytic leukemia with all-trans retinoic acid resulting in scrotal ulceration:a report of 2 cases[J]. Journal of Clinical Dermatology, 2003, 32(10): 612-613
Authors:ZHU Tie-shan  YU Bao-tian  DUAN Ming-hui  LIU Ji-hai  FAN Jing-bo
Abstract:Here report two cases of scrotal ulceration followed the treatment with all-trans retinoic acid for acute promyelo-cytic leukemia.These two patients with acute promyelocytic leukemia had scrotal ulceration19days and10days after treated with all-trans retinoic acid respectively.The ulceration was healed in both cases after stopping the use of all-trans retinoic acid and daily dressing change.
Keywords:acute promyelocytic leukemia  all-trans retinoic acid  scrotal ulceration  side effect
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