| 胃癌与胃溃疡病变的核仁组成区嗜银蛋白(Ag-NORs)定量研究 |
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| 引用本文： | 任毅,周德俊,王鹏志,李绍平. 胃癌与胃溃疡病变的核仁组成区嗜银蛋白(Ag-NORs)定量研究[J]. 天津医药, 1992, 0(8) |
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| 作者姓名： | 任毅 周德俊 王鹏志 李绍平 |
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| 作者单位： | 天津医学院附属医院普外科,天津医学院附属医院普外科,天津医学院附属医院普外科,天津肿瘤研究所免疫生化 300052,300052,300052 |
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| 摘 要： | 应用嗜银方法对18例肠型胃癌、16例胃溃疡、34例正常粘膜对照组进行了核仁组成区嗜银蛋白(Ag-NORs)的定量研究。在胃粘膜病变中Ag-NORs值随病变程度的加重而递增。Ag-NORs均值除对照的正常胃粘膜组(P>0.05)外,其余各病变组间Ag-NORs均值有显著性差异(P<0.01)。因此Ag-NORs计数可作为胃癌、胃溃疡鉴别的一种定量指标。
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| 关 键 词： | 核仁组成区 胃癌 胃溃疡 |
Quantitative Study on Ag-NORs in Nucleolar Organizer Regions in Gastric Cancer and Gastric Ulcer |
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| Ren Yi,et al. Quantitative Study on Ag-NORs in Nucleolar Organizer Regions in Gastric Cancer and Gastric Ulcer[J]. Tianjin Medical Journal, 1992, 0(8) |
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| Authors: | Ren Yi et al |
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| Affiliation: | Ren Yi,et al Department of Surgery,Tianjin Medical College Hospital |
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| Abstract: | Using a silver staining technique, Ag-NORs have been studied in paraffin sec-tions of 18 cases of "intestinal type" of gastric carcinoma, 16 gastric ulcer, and 34 nor-mal gastic mucosa served as control. The results showed that Ag-NORs count wasincreased along with the increase in the degree of atypism in the gastric mucosal lesions. Significant differences were found in the mean values of Ag-NORs count amongvarious groups except the normal control. Hence, it indicated that Ag-NORs could beused as a quantitative parameter for the differentiation of malignant from benigngastric lesions. |
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| Keywords: | nucleolar organizer regions gastric carcinoma gastric ulcer |
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